Discovering naturally processed antigenic determinants that confer protective T cell immunity

Authors :: Gilchuk, Pavlo
Spencer, Charles T.
Conant, Stephanie B.
Hill, Timothy
Gray, Jennifer J.
Niu, Xinnan
Zheng, Mu
Erickson, John J.
Boyd, Kelli L.
McAfee, K. Jill
Oseroff, Carla
Hadrup, Sine R.
Bennink, Jack R.
Hildebrand, William
Edwards, Kathryn M.
Crowe, Jr., James E.
Williams, John V.
Buus, Soren
Sette, Alessandro
Schumacher, Ton N.M.
Link, Andrew J.
Joyce, Sebastian
Source :: Journal of Clinical Investigation. May 1, 2013, Vol. 123 Issue 5, p1976, 12 p.
Publication Year :: 2013
Abstract: [CD8.sup.+] T cells (TCD8) confer protective immunity against many infectious diseases, suggesting that microbial TCD8 determinants are promising vaccine targets. Nevertheless, current T cell antigen identification approaches do not discern [...]

Subjects :: Physiological aspects
Research
Properties
Cellular immunity -- Research
Antigenic determinants -- Properties
T cells -- Physiological aspects

Full Text Access

Tools