PAR-1 contributes to the innate immune response during viral infection

Authors :: Antoniak, Silvio
Owens, III, A. Phillip
Baunacke, Martin
Williams, Julie C.
Lee, Rebecca D.
Weithauser, Alice
Sheridan, Patricia A.
Malz, Ronny
Luyendyk, James P.
Esserman, Denise A.
Trejo, JoAnn
Blaxall, Burns C.
Pawlinski, Rafal
Beck, Melinda A.
Rauch, Ursula
Mackman, Nigel
Source :: Journal of Clinical Investigation. March 1, 2013, Vol. 123 Issue 3, p1310, 13 p.
Publication Year :: 2013
Abstract: Coagulation is a host defense system that limits the spread of pathogens. Coagulation proteases, such as thrombin, also activate cells by cleaving PARs. In this study, we analyzed the role [...]

Subjects :: Immune response -- Health aspects -- Physiological aspects -- Genetic aspects -- Research
Cell receptors -- Physiological aspects -- Genetic aspects -- Research
Virus diseases -- Health aspects -- Development and progression -- Genetic aspects -- Research
Health care industry

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