Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice

Authors :: Baker, Nicki A.
Karounos, Michael
English, Victoria
Fang, Jun
Wei, Yinan
Stromberg, Arnold
Sunkara, Manjula
Morris, Andrew J.
Swanson, Hollie I.
Cassis, Lisa A.
Source :: Environmental Health Perspectives. January, 2013, Vol. 121 Issue 1, p105, 16 p.
Publication Year :: 2013
Abstract: BACKGROUND: Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in [...]

Subjects :: Gene expression -- Research -- Physiological aspects
Homeostasis -- Research -- Physiological aspects
Polychlorinated biphenyls -- Research -- Physiological aspects
Animal experimentation -- Usage
Weight loss -- Physiological aspects
Fat cells -- Research -- Physiological aspects
Environmental issues
Health

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