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Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation
Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation
- Source :
- Nature Medicine. May 1, 2013, Vol. 19 Issue 5, p640, 8 p.
- Publication Year :
- 2013
-
Abstract
- A shift from oxidative to glycolytic metabolism has been associated with skeletal muscle insulin resistance in type 2 diabetes (1-5). However, whether this metabolic switch is deleterious or adaptive remains [...]
- Subjects :
- Physiological aspects
Development and progression
Genetic aspects
Research
Risk factors
Skeletal muscle -- Physiological aspects -- Genetic aspects -- Research
Glucose metabolism -- Physiological aspects -- Genetic aspects -- Research
Type 2 diabetes -- Development and progression -- Genetic aspects -- Research
Insulin resistance -- Risk factors -- Genetic aspects -- Research
Muscles -- Physiological aspects -- Genetic aspects -- Research
Subjects
Details
- Language :
- English
- ISSN :
- 10788956
- Volume :
- 19
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.330826213
- Full Text :
- https://doi.org/10.1038/nm.3144