Early-onset, coexisting autoimmunity and decreased HLA-mediated susceptibility are the characteristics of diabetes in down syndrome

Authors :: Aitken, Rachel J.
Mehers, Kay L.
Williams, Alistair J.
Brown, Jamie
Bingley, Polly J.
Holl, Reinhard W.
Rohrer, Tilman R.
Schober, Edith
Abdul-Rasoul, Majedah M.
Shield, Julian P.H.
Gillespie, Kathleen M.
Source :: Diabetes Care. May, 2013, Vol. 36 Issue 5, p1181, 5 p.
Publication Year :: 2013
Abstract: OBJECTIVE--Down syndrome (DS) is associated with an increased risk of diabetes, particularly in young children. HLA-mediated risk is however decreased in children with DS and diabetes (DSD). We hypothesized that [...]

Subjects :: Autoimmunity
Diabetes -- Development and progression
Autoantibodies
Down syndrome -- Development and progression
Health

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