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Induction of pathogenic [T.sub.H]17 cells by inducible salt-sensing kinase SGK1

Authors :
Wu, Chuan
Yosef, Nir
Thalhamer, Theresa
Zhu, Chen
Xiao, Sheng
Kishi, Yasuhiro
Regev, Aviv
Kuchroo, Vijay K.
Source :
Nature. April 25, 2013, Vol. 496 Issue 7446, p513, 5 p.
Publication Year :
2013

Abstract

[T.sub.H]17 cells (interleukin-17 (IL-17)-producing helper T cells) are highly proinflammatory cells that are critical for clearing extracellular pathogens and for inducing multiple autoimmune diseases (1). IL-23 has a critical role [...]

Details

Language :
English
ISSN :
00280836
Volume :
496
Issue :
7446
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.329182546
Full Text :
https://doi.org/10.1038/nature11984