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Depressed levels of prostaglandin [F.sub.2α] in mice lacking Akrlb7 increase basal adiposity and predispose to diet-induced obesity

Authors :
Volat, Fanny E.
Pointud, Jean-Christophe
Pastel, Emilie
Morio, Beatrice
Sion, Benoit
Hamard, Ghislaine
Guichardant, Michel
Colas, Romain
Lefrancois-Martinez, Anne-Marie
Martinez, Antoine
Source :
Diabetes. November 1, 2012, Vol. 61 Issue 11, p2796, 11 p.
Publication Year :
2012

Abstract

Negative regulators of white adipose tissue (WAT) expansion are poorly documented in vivo. Prostaglandin [F.sub.2α] (PG[F.sub.2α]) is a potent antiadipogenic factor in cultured preadipocytes, but evidence for its involvement in [...]

Details

Language :
English
ISSN :
00121797
Volume :
61
Issue :
11
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.311048415
Full Text :
https://doi.org/10.2337/db11-1297