Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

Authors :: Fukushima, Yoko
Okada, Mitsuhiro
Kataoka, Hiroshi
Hirashima, Masanori
Yoshida, Yutaka
Mann, Fanny
Gomi, Fumi
Nishida, Kohji
Nishikawa, Shin-Ichi
Uemura, Akiyoshi
Source :: Journal of Clinical Investigation. May 1, 2011, Vol. 121 Issue 5, p1974, 12 p.
Publication Year :: 2011
Abstract: During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces without ameliorating retinal [...]

Subjects :: Neovascularization -- Research
Vascular endothelial growth factor -- Physiological aspects -- Research
Cellular signal transduction -- Research
Retinal diseases -- Development and progression -- Research
Health care industry

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