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Creation of a type 1 blue copper site within a de novo coiled-coil protein scaffold

Authors :
Shiga, Daigo
Nakane, Daisuke
Inomata, Tomohiko
Funahashi, Yasuhiro
Masuda, Hideki
Kikuchi, Akihiro
Oda, Masayuki
Noda, Masanori
Uchiyama, Susumu
Fukui, Kiichi
Kanaori, Kenji
Tajima, Kunihiko
Takano, Yu
Nakamura, Haruki
Tanaka, Toshiki
Source :
Journal of the American Chemical Society. Dec 29, 2010, Vol. 132 Issue 51, 18191-18198
Publication Year :
2010

Abstract

The article presents the formation of a new stable copper coordination scaffold, which is shown to consist of a four-standard [alpha]-helical coiled-coil structure. The protein bound copper site is shown to exhibit a blue color, UV-vis spectra.

Details

Language :
English
ISSN :
00027863
Volume :
132
Issue :
51
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.249542972