Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure

Authors :: Massie, Barry M.
O'Connor, Christopher M.
Metra, Marco
Ponikowski, Piotr
Teerlink, John R.
Cotter, Gad
Weatherley, Beth Davison
Cleland, John G.F.
Givertz, Michael M.
Voors, Adriaan
DeLucca, Paul
Mansoor, George A.
Salemo, Christina M.
Bloomfield, Daniel M.
Dittrich, Howard C.
Source :: The New England Journal of Medicine. Oct 7, 2010, Vol. 363 Issue 15, p1419, 10 p.
Publication Year :: 2010
Abstract: A study was conducted to evaluate the effect and benefits of the use of rolofylline, an adenosine A1-receptor antagonist in improving dyspnea and reducing the risk of renal failure in the case of patients with acute heart failure. Results indicated that rolofylline did not have any kind of favorable outcome in the case of such patients.