Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3

A genome-wide association study (GWAS) is conducted to identify the genetic variants associated with susceptibility to a multifactorial malignancy in humans called nasopharyngeal carcinoma (NPC). Results reveal that multiple single-nucleotide polymorphisms (SNPs) located within the HLA gene region at chromosome 6p21.3 are associated with NPC susceptibility in the Taiwanese populations examined.