Rapid molecular detection of tuberculosis and rifampin resistance

Authors :: Boehme, Catharina C.
Nabeta, Pamela
Hillermann, Doris
Nicol, Mark P.
Shenai, Shubhada
Krapp, Fiorella
Allen, Jenny
Tahirli, Rasim
Blakemore, Robert
Rustomjee, Roxana
Milovic, Ana
Jones, Martin
O'Brien, Sean M.
Persing, David H.
Ruesch-Gerdes, Sabine
Gotuzzo, Eduardo
Rodrigues, Camilla
Alland, David
Perkins, Mark D.
Source :: The New England Journal of Medicine. Sept 9, 2010, Vol. 363 Issue 11, p1005, 1015 p.
Publication Year :: 2010
Abstract: A study was conducted to evaluate the efficacy of Xpert MTB/RIF, an automated molecular detection test for myobacterium tuberculosis (MTB) and resistance to rifampin (RIF) in patients with suspected drug-sensitive tuberculosis. Results indicated that the test was highly effective in sensitive detection of tuberculosis and RIF resistance.