Copper-catalyzed multicomponent reaction: synthesis of 4-arylsulfonylimino-4,5-dihydrofuran derivatives

Authors :: Yongjia Shang
Kai Ju
Xinwei He
Jinsong Hu
Shuyan Yu
Min Zhang
Kaisheng Liao
Lifen Wang
Ping Zhang
Source :: Journal of Organic Chemistry. August 20, 2010, Vol. 75 Issue 16, 5743-5745
Publication Year :: 2010
Abstract: A series of 4-arylsulfonylimino-4,5-dihydrofurans are prepared by using copper-catalyzed three-component reaction between sulfonyl azides, phenylacetylene and [beta]-ketoesters in tetrahydrofuran (THF) in the presence of triethylamine (TEA). A plausible mechanism is proposed for the process.

Subjects :: Acetylene -- Chemical properties
Catalysis -- Analysis
Copper -- Chemical properties
Sulfones -- Chemical properties
Tetrahydrofuran -- Structure
Tetrahydrofuran -- Chemical properties
Biological sciences
Chemistry

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