Heptahelical receptors GprC and GprD of Aspergillus fumigatus are essential regulators of colony growth, hyphal morphogenesis, and virulence

Two putative G-protein-coupled receptors, GprC and GprD were characterized with respect to their cellular functions to understand the specific stimuli and the corresponding receptors activating the signaling cascades in the fungus Aspergillus fumigatus. The results demonstrated the role of the receptors towards the integration and processing stress signals via modulation of the calcineurin pathway.