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Powerful SNP-set analysis for case-control genome-wide association studies

Authors :
Wu, Michael C.
Kraft, Peter
Epstein, Michael P.
Taylor Deanne M.
Chanock, Stephen J.
Hunter, David J.
Xihong Lin
Source :
American Journal of Human Genetics. June 11, 2010, Vol. 86 Issue 6, p929, 14 p.
Publication Year :
2010

Abstract

The application of the genome-wide association studies (GWAS) for determining different genetic variants related to disease risk is analyzed. The use of the set-analysis approach for case-control GWAS is also discussed.

Subjects

Subjects :
Haploidy -- Analysis
Human genome -- Research
Single nucleotide polymorphisms -- Research
Cancer -- Genetic aspects
Cancer -- Research
Biological sciences

Details

Language :
English
ISSN :
00029297
Volume :
86
Issue :
6
Database :
Gale General OneFile
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
edsgcl.234196384

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