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Limbal stem-cell therapy and long-term corneal regeneration

Authors :
Rama, Paolo
Matuska, Stanislav
Paganoni, Giorgio
Spinelli, Alessandra
Luca, Michele De
Pellegrini, Graziella
Source :
The New England Journal of Medicine. July 8, 2010, Vol. 363 Issue 2, p147, 9 p.
Publication Year :
2010

Abstract

A study was conducted to examine the long-term clinical results of cell therapy in patients with burn-related corneal destruction associated with limbal stem-cell deficiency, a highly disabling ocular disease. The successful clinical results for the patients with limbal stem-cell deficiency who received cultured limbal stem-cell grafts for corneal transplantation revealed that cultures of limbal stem cells represent a source of cells for transplantation in the treatment of burn-induced destruction of the human cornea.

Details

Language :
English
ISSN :
00284793
Volume :
363
Issue :
2
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.233933409