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Antiretroviral regimens in pregnancy and breast-feeding in Botswana

Authors :
Shapiro, R.L.
Snowden, W.
Martinez-Tristani, M.
Mazhani, L.
Essex, M.
Souda, S.
Lubega, E.
Akhtar, M.
Wester, C.
Tuomola, R.
Sharma, U.
Handelsman, E.
Mburu, K.
Jayeoba, O.
Moko, E.
Leidner, J.
Powis, K.
Asmelash, A.
Tumbare, E.
Zwerski, S.
Makhema, J.
Moyo, S.
Thior, I.
McIntosh, K.
van Widenfelt, E.
Hughes, M.D.
Ogwu, A.
Kitch, D.
Lockman, S.
Moffat, C.
Source :
The New England Journal of Medicine. June 17, 2010, Vol. 362 Issue 24, p2282, 13 p.
Publication Year :
2010

Abstract

The study attempts to evaluate the most effective and safe highly active antiretroviral therapy (HAART) in preventing human immunedeficiency virus type -1 (HIV-1) transmission during pregnancy and breast-feeding. The results indicate that all regimes of HAART had positive outcomes in reducing HIV-1 transmission, with a overall rate of 1.1% between mother and infant.

Subjects

Subjects :
Highly active antiretroviral therapy -- Health aspects
HIV infection -- Drug therapy
HIV infection -- Prevention
Disease transmission -- Risk factors
Disease transmission -- Patient outcomes
Pregnancy -- Health aspects
Breast feeding -- Health aspects
HIV infection in pregnancy -- Drug therapy
HIV infection in pregnancy -- Prevention

Details

Language :
English
ISSN :
00284793
Volume :
362
Issue :
24
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.233088875

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