How does the reductase help To regulate the catalytic cycle of cytochrome P450 3A4 using the conserved water channel?

Authors :: Fishelovitch, Dan
SShaik, ason
Wolfson, Haim J.
Nussinov, Ruth
Source :: Journal of Physical Chemistry B. May 6, 2010, Vol. 114 Issue 17, 5964-5970
Publication Year :: 2010

Subjects :: Arginine -- Chemical properties
Cytochrome P-450 -- Chemical properties
Cytochrome P-450 -- Structure
Oxidoreductases -- Chemical properties
Oxidoreductases -- Structure
Protein binding -- Analysis
Chemicals, plastics and rubber industries

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