Distinct variants at LIN28B influence growth in height from birth to adulthood

Authors :: Widen, Elisabeth
Ripatti, Samuli
Cousminer, Diana L.
Surakka, Ida
Lappalainen, Tuuli
Jarvelin, Marjo-Riitta
Eriksson, Johan G.
Raitakari, Olli
Salomaa, Veikko
Sovio, Ulla
Hartikainen, Anna-Liisa
Pouta, Anneli
McCarthy, Mark I.
Osmond, Clive
Kajantie, Eero
Lehtimaki, Terho
Viikari, Jorma
Kahonen, Mika
Tyler-Smith, Chris
Freimer, Nelson
Hirschhorn, Joel N.
Peltonen, Leena
Palotie, Aarno
Source :: American Journal of Human Genetics. May 14, 2010, Vol. 86 Issue 5, p773, 10 p.
Publication Year :: 2010
Abstract: A unique resource of longitudinal childhood height data available in Finnish population cohorts was used to study the largely unknown genetic underpinnings of height growth. The partially correlated variants at LIN28B which influence the entire period of postnatal growth implied a critical role for LIN28B in the regulation of human growth.

Subjects :: Human growth -- Research
Stature -- Genetic aspects
Genetic regulation -- Analysis
Human population genetics -- Research
Biological sciences

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