Structural properties and dynamic behavior of nonfibrillar oligomers formed by PrP(106-126)

Authors :: Walsh, Patrick
Neudecker, Philipp
Sharpe, Simon
Source :: Journal of the American Chemical Society. June 9, 2010, Vol. 132 Issue 22, 7684-7695
Publication Year :: 2010
Abstract: Various studies are conducted to explain the structural properties, as well as the dynamics of the stable nonfibrillar oligomers that are formed by the human prion protein (PrP) residues. These oligomers are shown to be highly associated with various neurodegenerative diseases.

Subjects :: Glycoproteins -- Structure
Glycoproteins -- Chemical properties
Nuclear magnetic resonance spectroscopy -- Usage
Oligomers -- Chemical properties
Prions -- Structure
Prions -- Chemical properties
Nervous system -- Degeneration
Nervous system -- Research
Chemistry

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