A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1

A multistage strategy was used to obtain strong evidence for implication of the HIVEP1 locus as a candidate for venous thrombosis (VT) risk. The results provide first evidence for the role of a genetic variant on the risk of VT outside the traditional coagulation/fibrinolysis cascade.