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Solvent effects on catalysis by Escherichia coli dihydrofolate reductase

Authors :
Loveridge, E. Joel
Tey, Lai-Hock
Allemann, Rudolf K.
Source :
Journal of the American Chemical Society. Jan 27, 2010, Vol. 132 Issue 3, 1137-1143
Publication Year :
2010

Abstract

The article discusses the mechanisms, as well as the kinetics associated with the reaction catalyzed by dihydrofolate reductase obtained from Escherichia coli. The various effects of solvent composition on the temperature dependency of the various kinetic parameters are also explained.

Details

Language :
English
ISSN :
00027863
Volume :
132
Issue :
3
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.220102688