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Evolution of MRSA during hospital transmission and intercontinental spread
- Source :
- Science. Jan 22, 2010, Vol. 327 Issue 5964, p469, 6 p.
- Publication Year :
- 2010
-
Abstract
- Current methods for differentiating isolates of predominant lineages of pathogenic bacteria often do not provide sufficient resolution to define precise relationships. Here, we describe a high-throughput genomics approach that provides a high-resolution view of the epidemiology and microevolution of a dominant strain of methicillin-resistant Staphylococcus aureus (MRSA). This approach reveals the global geographic structure within the lineage, its intercontinental transmission through four decades, and the potential to trace person-to-person transmission within a hospital environment. The ability to interrogate and resolve bacterial populations is applicable to a range of infectious diseases, as well as microbial ecology. 10.1126/science.1182395
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 327
- Issue :
- 5964
- Database :
- Gale General OneFile
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.218527739
- Full Text :
- https://doi.org/10.1126/science.1182395