Genetic variants associated with Lp(a) lipoprotein level and coronary disease

Authors :: Clarke, Robert
Peden, John F.
Hopewell, Jemma C.
Kyriakou, Theodosios
Goel, Anuj
Heath, Simon C.
Parish, Sarah
Barlera, Simona
Franzosi, Maria Grazia
Rust, Stephan
Bennett, Derrick
Silveira, Angela
Malarstig, Anders
Green, Fiona R.
Lathrop, Mark
Gigante, Bruna
Leander, Karin
de Faire, Ulf
Seedorf, Udo
Hamsten, Anders
Collins, Rory
Watkins, Hugh
Farrall, Martin
Source :: The New England Journal of Medicine. Dec 24, 2009, Vol. 361 Issue 26, p2518, 11 p.
Publication Year :: 2009
Abstract: Several experimental studies are conducted to explain the genetic determinants that are associated with the Lp(a) lipoprotein level and the coronary disease in patients. The Lp(a) lipoprotein is shown to exhibit a significant role in the onset of the coronary disease.

Subjects :: Coronary heart disease -- Physiological aspects
Lipoprotein A -- Genetic aspects

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