Gastroesophageal reflux disease a clinical and endoscopic study of Nigerian patients

Background/Aims: Gastroesophageal reflux disease (GERD) occurs worldwide but its prevalence varies in different parts of the world. The main objectives of this study were to determine the spectrum of GERD and risk factors associated with it in Nigerians. Methods: Patients with upper gastrointestinal symptoms were administered Carlsson-Dent questionnaire to diagnose GERD. This was followed by standard upper gastrointestinal endoscopy. Results: Using the CD questionnaire GERD was diagnosed in 156 patients, but after upper endoscopy, only 40 patients (25.6%) had varying degrees of esophagitis. Body mass index correlated positively with GERD symptom score. Conclusion: Non erosive reflux disease is the predominant form of GERD seen in Nigerians. A symptom-driven patient-centered approach to the diagnosis of GERD is the best strategy that captures most cases. Body mass index has positive correlation with GERD. Keywords: Gastroesophageal reflux | esophagitis | Nigerians
Introduction Gastroesophageal reflux disease (GERD) is a common disorder of the upper gastrointestinal tract with an incidence of 10-38% of adults in the Western population (1,2). Previously it was thought [...]