Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease

Authors :: Sidransky, E.
Nalls, M.A.
Aasly, J.O.
Aharon-Peretz, J.
Annesi, G.
Barbosa, E.R.
Bar-Shira, A.
Berg, D.
Bras, J.
Brice, A.
C.-M. Chen
Clark, L.N.
Condroyer, C.
De Marco, E.V.
Eblan, M.J.
Fahn, S.
Farrer, M.J.
Durr, A.
H.-C. Fung
Gan-Or, Z.
Gasser, T.
Gershoni-Baruch R.
Giladi, N.
Griffith, A.
Gurevich, T.
Januario, C.
Kropp, P.
Lang, A.E.
C.-J. Lee Chen
Lesage, S.
Marder, K.
Mata, I.F.
Mirelman, A.
Mutsui, J.
Mizuta, I.
Nicoletti, G.
Oliveira, C.
Ottman, R.
Orr-Urteger, A.
Pereira, L.V.
Quattron, A.
Spitz, M.
E.-K. Tan
Tayebi, N.
Toda, T.
Troiano, S.
Tsuji, S.
Wittstock, M.
Wolfsberg, T.G.
Y.-R. Wu
Zabetian, C.P.
Y. Zhao
Ziegler, S.G.
Source :: The New England Journal of Medicine. Oct 22, 2009, Vol. 361 Issue 17, p1651, 11 p.
Publication Year :: 2009
Abstract: The study determines the frequency of glucocerebrosidase ("GBA") mutations in an ethnically diverse group of patients with Parkinson's disease. Findings indicate a strong relation between "GBA" mutations and Parkinson's disease.

Subjects :: Parkinson's disease -- Risk factors
Hydrolases -- Health aspects
Enzymes -- Health aspects

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