Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism

Subjects

Subjects :

Cytochrome P-450 -- Chemical properties
Cytochrome P-450 -- Structure
Hydrophobicity -- Analysis
Molecular dynamics -- Usage
Phenylalanine -- Structure
Phenylalanine -- Chemical properties
Solvation -- Analysis
Chemicals, plastics and rubber industries

Details

Language :

English

ISSN :

15206106

Volume :

113

Issue :

39

Database :

Gale General OneFile

Journal :

Journal of Physical Chemistry B

Publication Type :

Academic Journal

Accession number :

edsgcl.210553741