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Temporal and quantitative correlations between insulin secretion and stably elevated or oscillatory cytoplasmic Ca2+ in mouse pancreatic beta-cells

Authors :
Jonas, Jean-Christophe
Gilon, Patrick
Henquin, Jean-Claude
Source :
Diabetes. August 1998, Vol. 47 Issue 8, p1266, 8 p.
Publication Year :
1998

Abstract

An increase in cytoplasmic [Ca.sup.2+] in Β-cells is a key step in glucose-induced insulin secretion. However, whether changes in cytoplasmic free [Ca.sup.2+]. ([[[Ca.sup.2+]].sub.i]) directly regulate secretion remains disputed. This question [...]

Details

Language :
English
ISSN :
00121797
Volume :
47
Issue :
8
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.21048716