Fat balance in obese subjects: role of glycogen stores

Research was conducted to examine the hypothesis that obese subjects are less capable of speedily adjusting fat oxidation to fat intake on a high-fat (HF) diet particularly when exhaustive exercise decreases glycogen stores. Obese subjects were observed after they were switched to an HF diet from a reduced-fat diet to analyze the effect of low glycogen stores on fat oxidation. Results indicate that obese subjects can rapidly adjust fat oxidation to fat intake when exhaustive exercise lowers glycogen stores.