Preterm premature rupture of membranes: does the duration of latency influence perinatal outcomes?

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2009.07.045 Byline: Tracy A. Manuck, Courtney C. Maclean, Robert M. Silver, Michael W. Varner Keywords: expectant management; latency; perinatal outcome; prematurity; preterm premature rupture of membranes Abstract: Preterm premature rupture of membranes (PPROM) is the leading identifiable cause of prematurity. We hypothesized that, when controlled for delivery gestational age, potential prolonged exposure to inflammation/infection could be harmful to the developing fetus. Author Affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah, and Intermountain Healthcare Maternal Fetal Medicine, Salt Lake City, UT Article History: Received 23 February 2009; Revised 24 April 2009; Accepted 16 July 2009 Article Note: (footnote) Authorship and contribution to the article is limited to the 4 authors indicated. There was no outside funding or technical assistance with the production of this article., Cite this article as: Manuck TA, Maclean CC, Silver RM, et al. Preterm premature rupture of membranes: does the duration of latency influence perinatal outcomes? Am J Obstet Gynecol 2009;201:414.e1-6.