Polymorphisms in the promoter region of the interleukin-10 (IL-10) gene in women with cervical insufficiency

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2009.05.022 Byline: Jennifer E. Warren (a), Lesa M. Nelson (c), Gregory J. Stoddard (b), M. Sean Esplin (a), Michael W. Varner (a), Robert M. Silver (a) Keywords: cervical insufficiency; IL-10; inflammation; polymorphisms Abstract: Our objective was to determine whether polymorphisms in the promoter region of the interleukin-10 gene are more common in women with cervical insufficiency compared with controls. Author Affiliation: (a) Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah (b) Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah (c) Taueret Laboratories, Salt Lake City, Utah Article History: Received 2 September 2008; Revised 12 February 2009; Accepted 14 May 2009 Article Note: (footnote) Cite this article as: Warren JE, Nelson LM, Stoddard GJ, et al. Polymorphisms in the promoter region of the interleukin-10 (IL-10) gene in women with cervical insufficiency. Am J Obstet Gynecol 2009;201:372.e1-5.