Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes

Authors :: Larsen, Claus M.
Faulenbach, Mirjam
Vaag, Allan
Ehses, Jan A.
Donath, Marc Y.
Mandrup-poulsen, Thomas
Source :: Diabetes Care. September 2009, Vol. 32 Issue 9, p1663, 6 p.
Publication Year :: 2009
Abstract: OBJECTIVE--Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is increased and interleukin-1 receptor antagonist (IL-1Ra) expression reduced in patients with type 2 diabetes. Treatment with [...]

Subjects :: C-reactive protein -- Measurement -- Control -- Research -- Health aspects -- Usage
Type 2 diabetes -- Drug therapy -- Research
Interleukin-1 -- Health aspects -- Control -- Research -- Measurement -- Usage
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