Synthesis of a BODIPY library and its application to the development of live cell glucagon imaging probe

Authors :: Jun-Seok Lee
Nam-young Kang
Yun Kyung Kim
Samanta, Animesh
Suihan Feng
Hyeong Kyu Kim
Vendrell, Marc
Jung Hwan Park
Young-Tae Chang
Source :: Journal of the American Chemical Society. July 29, 2009, Vol. 131 Issue 29, 10077-10082
Publication Year :: 2009
Abstract: The first BODIPY library (BD) is prepared via a Knoevenagel-type condensation reaction and a highly selective glucagon sensor (Glucagon Yellow (BD-105)) is discovered by fluorescence image-based screening method. The results have shown the application of Glucagon Yellow as a glucagon imaging agent in live cells and tissues.

Subjects :: Diagnostic imaging -- Usage
Fluorescence -- Evaluation
Glucagon -- Chemical properties
Liver cells -- Physiological aspects
Chemistry

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