Structures of the phosphorylated and V[O.sub.3]-bound 2H-phosphatase domain of Sts-2

Authors :: Yunting Chen
Jakoncic, Jean
Parker, Kathlyn A.
Carpino, Nick
Nassar, Nicolas
Source :: Biochemistry. Sept 1, 2009, Vol. 48 Issue 34, 8129-8135
Publication Year :: 2009
Abstract: The article studies crystal structure of Sts-[2.sub.PGM] in the phosphorylated active form and bound to V[O.sub.3]. Findings suggest a role for Glu476 in activating a uniquely positioned water molecule.

Subjects :: Enzyme binding -- Analysis
Glutamine -- Chemical properties
Phosphatases -- Chemical properties
Phosphatases -- Structure
Phosphorylation -- Analysis
Biological sciences
Chemistry

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