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BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones

Authors :
Souza, Sandra C.
Yamamoto, Mia T.
Franciosa, Mark D.
Lien, Ping
Greenberg, Andrew S.
Source :
Diabetes. April 1998, Vol. 47 Issue 4, p691, 5 p.
Publication Year :
1998

Abstract

Thiazolidinediones (TZDs) such as BRL 49653 are a class of antidiabetic agents that are agonists for the peroxisome proliferator-activated nuclear receptor (PPAR-[Gamma]2). In vivo, TZDs reduce circulating levels of free [...]

Details

Language :
English
ISSN :
00121797
Volume :
47
Issue :
4
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.20555754