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Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma

Authors :
Gleave, Martin E.
Elhilali, Mostafa
Fradet, Yves
Davis, Ian
Venner, Peter
Saad, Fred
Klotz, Laurence H.
Moore, Malcolm J.
Paton, Virginia
Bajamonde, Alex
Source :
The New England Journal of Medicine. April 30, 1998, Vol. v338 Issue n18, p1265, 7 p.
Publication Year :
1998

Abstract

Interferon gamma-1b does not appear to improve the prognosis of patients with a type of kidney cancer called renal-cell carcinoma. Researchers gave 181 patients with renal-cell carcinoma weekly injections of interferon gamma-1b or a placebo. All the patients had metastatic cancer and the primary tumor had been treated. Only 4.4% of those receiving interferon gamma-1b responded, compared to a 6.6% response rate in those receiving a placebo. Interferon gamma-1b did not reduce disease progression or improve survival rates.

Details

ISSN :
00284793
Volume :
v338
Issue :
n18
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.20554353