Identification of Type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon

A comparative study was conducted on extracellular protein profiles from wild-type and regulatory or secretory isogenic mutants of the Pseudomonas aeruginosa exoenzyme S regulon to identify proteins coordinately secreted with ExoS. P aeruginosa homologs to proteins of Yersinia spp that act as regulators of the low calcium response, regulators of secretion, and mediators of the type III translocation mechanism were identified.