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Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients

Authors :
Kristiansen, Ole Peter
Zamani, Mahdi
Johannesen, Jesper
Mandrup-Poulsen, Thomas
Cassiman, Jean-Jacques
Nerup, Jorn
Pociot, Flemming
Source :
Diabetes. February 1998, Vol. 47 Issue 2, p281, 3 p.
Publication Year :
1998

Abstract

[CD4.sup.+] T-cells play a central role in IDDM pathogenesis (1). Hence, gene polymorphisms that modulate the [CD4.sup.+] T-cell response to antigen presentation may confer susceptibility to IDDM. The CD4 receptor [...]

Details

Language :
English
ISSN :
00121797
Volume :
47
Issue :
2
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.20318182