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Suzuki-Miyaura cross-coupling reactions of primary alkyltrifluoroborates with aryl chlorides

Authors :
Dreher, Spencer D.
Siang-Ee Lim
Sandrock, Deirde L.
Molander, Gary A.
Source :
Journal of Organic Chemistry. May 15, 2009, Vol. 74 Issue 10, 3626-3631
Publication Year :
2009

Abstract

Parallel microscale experimentation is used for developing general conditions for the Suzuki-Miyaura cross-coupling of diversely functionalized primary alkyltrifluoroborates with a variety of aryl chlorides. The conditions obtained are amenable to coupling with aryl bromides, iodides and triflates.

Details

Language :
English
ISSN :
00223263
Volume :
74
Issue :
10
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.203160803