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Anaesthetics set their sites on ion channels

Anaesthetics set their sites on ion channels

Authors :
Franks, N.P.
Lieb, W.R.
Source :
Nature. Sept 25, 1997, Vol. 389 Issue 6649, p334, 2 p.
Publication Year :
1997

Abstract

The main inhibitory neurotransmitters in the spinal cord and brain are glycine and gamma-aminobutyric acid and the function of their respective receptor brain proteins are enhanced by anaesthetics which reduce the functions of related receptors. Chimaeric constructs are used to support the theory that general anaesthetics are not nonspecific as previously thought.

Details

ISSN :
00280836
Volume :
389
Issue :
6649
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.20073736