Back to Search
Start Over
Prospective study of coffee consumption and risk of Parkinson's disease
- Source :
- European Journal of Clinical Nutrition. July, 2008, Vol. 62 Issue 7, p908, 8 p.
- Publication Year :
- 2008
-
Abstract
- Objective: To examine the prediction of coffee consumption on the incidence of Parkinson&apos;s disease. Subjects and methods: The study population comprised 6710 men and women, aged 50-79 years and free from Parkinson&apos;s disease at the baseline. At baseline, enquiries were made about coffee consumption in a self-administered questionnaire as the average number of cups per day. During a 22-year follow-up, 101 incident cases of Parkinson&apos;s disease occurred. Parkinson&apos;s disease cases were identified through a nationwide registry of patients receiving medication reimbursement, which is based on certificates from neurologist. Results: After adjustments for age, sex, marital status, education, community density, alcohol consumption, leisure-time physical activity, smoking, body mass index, hypertension and serum cholesterol, the relative risk for subjects drinking 10 or more cups of coffee per day compared with non-drinkers was 0.26 (95% confidence interval 0.07-0.99, P-value for trend =0.18). The association was stronger among overweight persons and among persons with lower serum cholesterol level (P-value for interaction= 0.04 and 0.03, respectively). Conclusions: The results support the hypothesis that coffee consumption reduces the risk of Parkinson&apos;s disease, but protective effect of coffee may vary by exposure to other factors. doi:10.1038/sj.ejcn.1602788; published online 16 May 2007 Keywords: coffee; cohort studies; Parkinson&apos;s disease<br />Introduction As the age of the general population is increasing, the prevalence of Parkinson's disease is projected to rise in future (Lang and Lozano, 1998). Although the etiology of Parkinson's [...]
- Subjects :
- Parkinson's disease -- Prevention
Coffee -- Health aspects
Subjects
Details
- Language :
- English
- ISSN :
- 09543007
- Volume :
- 62
- Issue :
- 7
- Database :
- Gale General OneFile
- Journal :
- European Journal of Clinical Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.197929459