The development and application of a monoclonal antibody purification platform: a purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies

Authors :: Glynn, Judy
Hagerty, Timothy
Pabst, Timothy
Annathur, Gopinath
Thomas, Kristin
Johnson, Paul
Ramasubramanyan, Natarajan
Mensah, Paul
Source :: Biopharm International. March, 2009, Vol. 22 Issue 3, pS16, 5 p.
Publication Year :: 2009
Abstract: ABSTRACT The following article describes the development of a purification platform for monoclonal antibodies (MAbs) at Pfizer's Global Biologics division, including how the individual unit operations have been affected by [...]

Subjects :: Biological products industry -- Health aspects
Immunoglobulins -- Health aspects
Biopharmaceutics -- Health aspects
Enzyme-linked immunosorbent assay -- Health aspects
Monoclonal antibodies -- Health aspects
Cell research -- Health aspects
Biotechnology industry
Business
Pharmaceuticals and cosmetics industries

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