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An easy approach to the synthesis of optically active vic-diols: a new single -enzyme system
- Source :
- Journal of Organic Chemistry. March 21, 1997, Vol. 62 Issue 6, p1854, 3 p.
- Publication Year :
- 1997
-
Abstract
- A novel method for the synthesis of chiral 1,2-diols is described. The scheme involves the reduction of the corresponding alpha-diketones with the reduced form of nicotinamide adenine nucleotide. The reaction is catalyzed by a diacetyl reductase from Bacillus stearothemophilus. The conditions and mechanisms for the reactions are presented.
Details
- ISSN :
- 00223263
- Volume :
- 62
- Issue :
- 6
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.19511847