Effects of dexamethasone on the uterine and umbilical vascular beds during basal and hypoxemic conditions in sheep

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2003.09.046 Byline: Juanita K Jellyman, David S Gardner, Abigail L Fowden, Dino A Giussani Keywords: Dexamethasone; uterine blood flow; umbilical blood flow Abstract: The purpose of the study was to test the hypotheses that maternal treatment with dexamethasone leads to a reduction in basal umbilical blood flow and diminishes the fetal umbilical hemodynamic response to acute hypoxemic stress in sheep. Author Affiliation: Physiological Laboratory, University of Cambridge, Cambridge, UK Article History: Received 26 June 2003; Revised 10 September 2003; Accepted 15 September 2003 Article Note: (footnote) [star] Supported by Tommy's: The Baby Charity, United Kingdom. Dr Giussani is a Fellow of The Lister Institute for Preventive Medicine, United Kingdom.