BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) randomized trial

Authors :: Rickli, Hans
Pfisterer, Matthias
Buser, Peter
Gutmann, Marc
Erne, Paul
Rickenbacher, Peter
Vuillomenet, Andre
Jeker, Urs
Dubach, Paul
Beer, Hansjurg
Se-Il Yoon
Suter, Thomas
Osterhues, Hans H.
Schieber, Michael M.
Hilti, Patrick
Schindler, Ruth
Rocca, Hans-Peter Brunner-La
Source :: JAMA, The Journal of the American Medical Association. Jan 28, 2009, Vol. 301 Issue 4, p383, 10 p.
Publication Year :: 2009
Abstract: A randomized trial called the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) investigated whether N-terminal brain natriuretic peptide (BNP)-guided heart failure therapy was more effective than symptom-guided therapy. Results suggested that BNP-guided therapy did not result in improved clinical outcomes when compared to symptom-guided therapy.

Subjects :: Heart failure -- Care and treatment
Aged patients -- Health aspects
Aged patients -- Care and treatment

Tools