The recA gene from Clostridium perfringens is induced by methyl methanesulphonate and contains an upstream Cheo box

The biochemical properties of the recA gene from Clostridium perfringens were analyzed to determine the genetic mechanisms involved in microbial homologous recombination and DNA repair. Analysis of Clostridium perfringens recA gene indicated the role of DNA damage in activating the RecA protein due to exposure of the cells to methyl methanesulphonate. Furthermore, induction of recA gene due to DNA damage in Clostridium perfringens was also mediated by the presence of an SOS-like Cheo box operator in the upstream region.