Interplay between oxidation state and coordination geometry of metal ions in azurin

The small electron transporting copper protein azurin was analyzed to study the interaction between the oxidation states of the metal and its coordination geometry. Findings indicated that the metal coordination geometry for Ag(I) in Ag(I) substituted wild-type azurin is only slightly different from the geometry for Cd(II) in cadmium-substituted azurin both being similar to the geometry for copper in native azurin.