Dynein Swings into Action

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.cell.2009.01.026 Byline: Anne Houdusse (1)(2), Andrew P. Carter (3) Abstract: Motor proteins, such as dynein, use chemical energy from ATP hydrolysis to move along the cytoskeleton. now describe the arrangement of subdomains in the motor domain of dynein and propose a model for how these regions function together in force generation. Author Affiliation: (1) Structural Motility Team, Institut Curie, Centre de Recherche, Paris F-75248, France (2) CNRS, UMR144, Paris F-75248, France (3) Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA