Palladium-catalyzed [gamma]-selective and stereospecific allyl-aryl coupling between allylic acetates and arylboronic acids

An air-tolerable, Pd-catalyzed [gamma]-selective and stereospecific substitution reaction between allylic acetates and arylboronic acids is described, which has produced allyl-aryl coupling products with a stereogenic center at the benzylic position. The reaction mechanism and development of more advanced catalyst system and enantioselective reactions with a chiral catalyst is being explored.