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Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1

Authors :
Amodeo, Gabriele A.
Rudolph, Michael J.
Tong, Liang
Source :
Nature. September 27, 2007, Vol. 449 Issue 7161, p492, 5 p.
Publication Year :
2007

Abstract

AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis in mammals and is an attractive target for drug discovery against diabetes, obesity and other diseases (1-5). The AMPK [...]

Details

Language :
English
ISSN :
00280836
Volume :
449
Issue :
7161
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.189796652